Morita H, Kohno J, Hori M, Kitano Y. Clinical application of low reactive level laser therapy (LLLT) for atopic dermatitis. Keio J Med. 1993;42(4):174-176. doi:10.2302/kjm.42.174
Hamblin MR, Nelson ST, Strahan JR. Photobiomodulation and Cancer: What Is the Truth? Photomed Laser Surg. 2018 May;36(5):241-245. doi: 10.1089/pho.2017.4401. Epub 2018 Feb 21. PMID: 29466089; PMCID: PMC5946726.
Pereira, S.T., Silva, C.R., Nuñez, S.C. and Ribeiro, M.S. (2021), Safety and Clinical Impact of a Single Red Light Irradiation on Breast Tumor-Bearing Mice. Photochem Photobiol, 97: 435-442.
https://doi.org/10.1111/php.13338
** Ken Tan1, Hyup-Woo Lee1,2, Seung-Kyu Han1 Effect of Low-Level Laser Therapy on Proliferation and Collagen Synthesis of Human Fibroblasts in Vitro
Journal of Wound Management and Research 2018; 14(1): 1-6.
Published online: March 30, 2018. DOI: https://doi.org/10.22467/jwmr.2018.00283 Huiling Ma1, Jong-Phil Yang1, Rui
Aguida B, Pooam M, Ahmad M, Jourdan N. Infrared light therapy relieves TLR-4 dependent hyper-inflammation of the type induced by COVID-19. Commun Integr Biol. 2021 Sep 15;14(1):200-211. doi: 10.1080/19420889.2021.1965718. PMID: 34552685; PMCID: PMC8451450.
Effective for increasing immunity, helping tissue repair, reducing pro-inflammatory cytokines. Read more citations here:
Zhu, S., Ma, X., Ding, X. et al. Comparative evaluation of low-level light therapy and ethinyl estradiol and desogestrel combined oral contraceptive for clinical efficacy and regulation of serum biochemical parameters in primary dysmenorrhoea: a prospective randomised multicentre trial. Lasers Med Sci 37, 2239–2248 (2022). https://doi.org/10.1007/s10103-021-03490-z
Lee JM, Kim KH. Effect of near-infrared rays on female menstrual pain in Korea. Nurs Health Sci. 2017 Sep;19(3):366-372. doi: 10.1111/nhs.12356. Epub 2017 Jul 7. PMID: 28686000.
The results of this study indicate that the near-infrared ray LED belt was effective in reducing menstrual pain and menstrual pain duration compared to the use of analgesics in Korean women with dysmenorrhea. Therefore, near-infrared rays may be used to relieve menstrual pain and improve the quality of life of women with dysmenorrhea.
Oliveira CG, Freitas MF, de Sousa MVP, Giorgi R, Chacur M. Photobiomodulation reduces nociception and edema in a CFA-induced muscle pain model: effects of LLLT and LEDT. Photochem Photobiol Sci. 2020;19(10):1392-1401. doi:10.1039/d0pp00037j
https://pubmed.ncbi.nlm.nih.gov/11776448/
Whelan HT, Smits RL Jr, Buchman EV, Whelan NT, Turner SG, Margolis DA, Cevenini V, Stinson H, Ignatius R, Martin T, Cwiklinski J, Philippi AF, Graf WR, Hodgson B, Gould L, Kane M, Chen G, Caviness J. Effect of NASA light-emitting diode irradiation on wound healing. J Clin Laser Med Surg. 2001 Dec;19(6):305-14. doi: 10.1089/104454701753342758. PMID: 11776448.
Hartmann DD, Martins RP, Silva TCD, et al. Oxidative stress is involved in LLLT mechanism of action on skin healing in rats.Braz J Med Biol Res. 2021;54(6):e10293. Published 2021 Apr 26. doi:10.1590/1414-431X202010293
Kenareh R, Mirmohammadi SJ, Khatibi A, Shamsi F, Mehrparvar AH. The Comparison of The Efficacy of Photobiomodulation and Ultrasound in the Treatment of Chronic Non-specific Neck Pain: A Randomized Single-Blind Controlled Trial. Journal of Lasers in Medical Sciences. 2021 ;12:e20. DOI: 10.34172/jlms.2021.20. PMID: 34733743; PMCID: PMC8558734.
https://journals.sagepub.com/doi/pdf/10.2203/dose-response.14-032.Agrawal
José Carlos Tatmatsu-Rocha, Cleber Ferraresi, Michael R. Hamblin, Flávio Damasceno Maia, Nilberto Robson Falcão do Nascimento, Patricia Driusso, Nivaldo Antonio Parizotto,
Low-level laser therapy (904nm) can increase collagen and reduce oxidative and nitrosative stress in diabetic wounded mouse skin,
Journal of Photochemistry and Photobiology B: Biology,
Volume 164,
2016,
Pages 96-102,
ISSN 1011-1344,
https://doi.org/10.1016/j.jphotobiol.2016.09.017.
(https://www.sciencedirect.com/science/article/pii/S101113441530172X)
Spitler R, Ho H, Norpetlian F, et al. Combination of low level light therapy and nitrosyl-cobinamide accelerates wound healing.J Biomed Opt. 2015;20(5):051022. doi:10.1117/1.JBO.20.5.051022
Whelan HT, Smits RL Jr, Buchman EV, Whelan NT, Turner SG, Margolis DA, Cevenini V, Stinson H, Ignatius R, Martin T, Cwiklinski J, Philippi AF, Graf WR, Hodgson B, Gould L, Kane M, Chen G, Caviness J. Effect of NASA light-emitting diode irradiation on wound healing. J Clin Laser Med Surg. 2001 Dec;19(6):305-14. doi: 10.1089/104454701753342758.
M, Chen G, Caviness J. Effect of NASA light-emitting diode irradiation on wound healing. J Clin Laser Med Surg. 2001 Dec;19(6):305-14. doi: 10.1089/104454701753342758.
Hartmann DD, Martins RP, Silva TCD, et al. Oxidative stress is involved in LLLT mechanism of action on skin healing in rats. Braz J Med Biol Res. 2021;54(6):e10293. Published 2021 Apr 26. doi:10.1590/1414-431X202010293.
José Carlos Tatmatsu-Rocha, et al. Low-level laser therapy (904nm) can increase collagen and reduce oxidative and nitrosative stress in diabetic wounded mouse skin, Journal of Photochemistry and Photobiology B: Biology, Volume 164, 2016, Pages 96-102, ISSN 1011-1344, doi: 10.1016/j.jphotobiol.2016.09.01.
Salman Yazdi R, Bakhshi S, Jannat Alipoor F, Akhoond MR, Borhani S, Farrahi F, Lotfi Panah M, Sadighi Gilani MA. Effect of 830-nm diode laser irradiation on human sperm motility. Lasers Med Sci. 2014 Jan;29(1):97-104. doi: 10.1007/s10103-013-1276-7. Epub 2013 Feb 14. PMID: 23407899.
Kenareh R, Mirmohammadi SJ, Khatibi A, Shamsi F, Mehrparvar AH. The Comparison of The Efficacy of Photobiomodulation and Ultrasound in the Treatment of Chronic Non-specific Neck Pain: A Randomized Single-Blind Controlled Trial. Journal of Lasers in Medical Sciences. 2021 ;12:e20. DOI: 10.34172/jlms.2021.20.
Acute Low Back Pain with Radiculopathy: A Double-Blind, Randomized, Placebo-Controlled Study
Ljubica M. Konstantinovic, Zeljko M. Kanjuh, Andjela N. Milovanovic, Milisav R. Cutovic, Aleksandar G. Djurovic, Viktorija G. Savic, Aleksandra S. Dragin, and Nesa D. Milovanovic
Photomedicine and Laser Surgery 2010 28:4, 553-560
Ishaq Ahmed, Mohammad Ali Mohseni Bandpei, Syed Amir Gilani, Ashfaq Ahmad, Faryal Zaidi, “Effectiveness of Low-Level Laser Therapy in Patients with Discogenic Lumbar Radiculopathy: A Double-Blind Randomized Controlled Trial”, Journal of Healthcare Engineering, vol. 2022, Article ID 6437523, 11 pages, 2022. https://doi.org/10.1155/2022/6437523
Wu S, Su Y, Wang L, Sun B, Jiang X. The effects of photobiomodulation therapy on inflammatory mediators, immune infiltration, and angiogenesis in a mouse model of rosacea. Ann Transl Med. 2022 Aug;10(15):831. doi: 10.21037/atm-22-3204. PMID: 36035005; PMCID: PMC9403938.
European College of Neuropsychopharmacology (ECNP). “Lack of interest in sex successfully treated by exposure to bright light.” ScienceDaily. ScienceDaily, 18 September 2016. <www.sciencedaily.com/releases/2016/09/160918214443.htm>.
Figueiro Longo MG, Tan CO, Chan ST, et al. Effect of Transcranial Low-Level Light Therapy vs Sham Therapy Among Patients With Moderate Traumatic Brain Injury: A Randomized Clinical Trial. JAMA Netw Open. 2020;3(9):e2017337. Published 2020 Sep 1. doi:10.1001/jamanetworkopen.2020.17337
Kenareh R, Mirmohammadi SJ, Khatibi A, Shamsi F, Mehrparvar AH. The Comparison of The Efficacy of Photobiomodulation and Ultrasound in the Treatment of Chronic Non-specific Neck Pain: A Randomized Single-Blind Controlled Trial. Journal of Lasers in Medical Sciences. 2021 ;12:e20. DOI: 10.34172/jlms.2021.20.
Ljubica M. Konstantinovic, Zeljko M. Kanjuh, Andjela N. Milovanovic, Milisav R. Cutovic, Aleksandar G. Djurovic, Viktorija G. Savic, Aleksandra S. Dragin, and Nesa D. Milovanovic
Photomedicine and Laser Surgery 284-553-560
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2. Hamblin MR. Can osteoarthritis be treated with light? Arthritis Res Ther 2013;15.
3. Tomazoni SS, Leal-Junior ECP, Pallotta RC, et al. Effects of photobiomodulation therapy, pharmacological therapy, and physical exercise as single and/or combined treatment on the inflammatory response induced by experimental osteoarthritis. Lasers Med Sci 2017;32:101–8.
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5. Wang P, Liu C, Yang X, et al. Effects of low-level laser therapy on joint pain, synovitis, anabolic, and catabolic factors in a progressive osteoarthritis rabbit model. Lasers Med Sci 2014;29:1875–85.
6. Assis L, Almeida T, Milares LP, et al. Musculoskeletal atrophy in an experimental model of knee osteoarthritis: the effects of exercise training and low-level laser therapy. Am J Phys Med Rehabil 2015;94:609–16.
7. Pallotta RC, Bjordal JM, Frigo L, et al. Infrared (810-nm) low-level laser therapy on rat experimental knee inflammation. Lasers Med Sci 2012;27:71–8.
Spitler R, Ho H, Norpetlian F, et al. Combination of low level light therapy and nitrosyl-cobinamide accelerates wound healing. J Biomed Opt. 2015;20(5):051022. doi:10.1117/1.JBO.20.5.051022
Whelan HT, Smits RL Jr, Buchman EV, Whelan NT, Turner SG, Margolis DA, Cevenini V, Stinson H, Ignatius R, Martin T, Cwiklinski J, Philippi AF, Graf WR, Hodgson B, Gould L, Kane M, Chen G, Caviness J. Effect of NASA light-emitting diode irradiation on wound healing. J Clin Laser Med Surg. 2001 Dec;19(6):305-14. doi: 10.1089/104454701753342758.
Whelan HT, Smits RL Jr, Buchman EV, Whelan NT, Turner SG, Margolis DA, Cevenini V, Stinson H, Ignatius R, Martin T, Cwiklinski J, Philippi AF, Graf WR, Hodgson B, Gould L, Kane M, Chen G, Caviness J. Effect of NASA light-emitting diode irradiation on wound healing. J Clin Laser Med Surg. 2001 Dec;19(6):305-14. doi: 10.1089/104454701753342758.
Hartmann DD, Martins RP, Silva TCD, et al. Oxidative stress is involved in LLLT mechanism of action on skin healing in rats. Braz J Med Biol Res. 2021;54(6):e10293. Published 2021 Apr 26. doi:10.1590/1414-431X202010293.
José Carlos Tatmatsu-Rocha, et al. Low-level laser therapy (904nm) can increase collagen and reduce oxidative and nitrosative stress in diabetic wounded mouse skin, Journal of Photochemistry and Photobiology B: Biology, Volume 164, 2016, Pages 96-102, ISSN 1011-1344, doi: 10.1016/j.jphotobiol.2016.09.01.
Cotler HB. A NASA discovery has current applications in orthopaedics. Curr Orthop Pract. 2015;26(1):72-74. doi:10.1097/BCO.0000000000000196.
Jackson, R. F., Dedo, D. D., Roche, G. C., Turok, D. I., & Maloney, R. J. (2009). Low-level laser therapy as a non-invasive approach for body contouring: A randomized, controlled study. Lasers in Surgery and Medicine, 41(10), 799–809. doi:10.1002/lsm.20855
https://sci-hub.se/10.1002/lsm.20855
McRae E, Boris J. Independent evaluation of low-level laser therapy at 635 nm for non-invasive body contouring of the waist, hips, and thighs. Lasers Surg Med. 2013 Jan;45(1):1-7. doi: 10.1002/lsm.22113. PMID: 23355338.
Cassano P, Petrie SR, Mischoulon D, Cusin C, Katnani H, Yeung A, De Taboada L, Archibald A, Bui E, Baer L, Chang T, Chen J, Pedrelli P, Fisher L, Farabaugh A, Hamblin MR, Alpert JE, Fava M, Iosifescu DV. Transcranial Photobiomodulation for the Treatment of Major Depressive Disorder. The ELATED-2 Pilot Trial. Photomed Laser Surg. 2018 Dec;36(12):634-646. doi: 10.1089/pho.2018.4490. Epub 2018 Oct 20. PMID: 30346890; PMCID: PMC7864111.
Ohshiro T. Personal Overview of the Application of LLLT in Severely Infertile Japanese Females. Laser Ther. 2012;21(2):97-103 doi:10.5978/islsm.12-OR-05.
Wunsch, Alexander, and Karsten Matuschka. “A controlled trial to determine the efficacy of red and near-infrared light treatment in patient satisfaction, reduction of fine lines, wrinkles, skin roughness, and intradermal collagen density increase.” Photomedicine and laser surgery vol. 32,2 (2014): 93-100. doi:10.1089/pho.2013.3616
Salman Yazdi R, Bakhshi S, Jannat Alipoor F, Akhoond MR, Borhani S, Farrahi F, Lotfi Panah M, Sadighi Gilani MA. Effect of 830-nm diode laser irradiation on human sperm motility. Lasers Med Sci. 2014 Jan;29(1):97-104. doi: 10.1007/s10103-013-1276-7. Epub 2013 Feb 14. PMID: 23407899.
Morita H, Kohno J, Hori M, Kitano Y. Clinical application of low reactive level laser therapy (LLLT) for atopic dermatitis. Keio J Med. 1993;42(4):174-176. doi:10.2302/kjm.42.174
Oliveira CG, Freitas MF, de Sousa MVP, Giorgi R, Chacur M. Photobiomodulation reduces nociception and edema in a CFA-induced muscle pain model: effects of LLLT and LEDT. Photochem Photobiol Sci. 2020;19(10):1392-1401. doi:10.1039/d0pp00037j
Agrawal T, Gupta GK, Rai V, Carroll JD, Hamblin MR. Pre-Conditioning with Low-Level Laser (Light) Therapy: Light before the Storm. Dose-Response. October 2014. doi:10.2203/dose-response.14-032.Agrawal.
Pillai JK, Mysore V. Role of Low-Level Light Therapy (LLLT) in Androgenetic Alopecia. J Cutan Aesthet Surg. 2021;14(4):385-391. doi:10.4103/JCAS.JCAS_218_20
Mai-Yi Fan, Sabrina PhD*; Cheng, Yu-Pin MD†; Lee, Ming-Yung PhD‡; Lin, Sung-Jan MD, PhD*,§,‖,¶; Chiu, Hsien-Yi MD, PhD*,§,**. Efficacy and Safety of a Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Self-Comparison, Sham Device-Controlled Trial. Dermatologic Surgery: November 2018 – Volume 44 – Issue 11 – p 1411-1420
Figueiro Longo MG, Tan CO, Chan ST, et al. Effect of Transcranial Low-Level Light Therapy vs Sham Therapy Among Patients With Moderate Traumatic Brain Injury: A Randomized Clinical Trial. JAMA Netw Open. 2020;3(9):e2017337. Published 2020 Sep 1. doi:10.1001/jamanetworkopen.2020.17337
Wagner H, Cheng JW, Ko EY. Role of reactive oxygen species in male infertility: An updated review of literature. Arab J Urol. 2017;16(1):35-43. Published 2017 Dec 8. doi:10.1016/j.aju.2017.11.001
Hamblin MR. Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophys. 2017;4(3):337-361. doi:10.3934/biophy.2017.3.337
Sommer AP. Mitochondrial cytochrome c oxidase is not the primary acceptor for near infrared light-it is mitochondrial bound water: the principles of low-level light therapy. Ann Transl Med. 2019 Mar;7(Suppl 1):S13. doi: 10.21037/atm.2019.01.43. PMID: 31032294; PMCID: PMC6462613.